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Phenotype Images associated with this Allele
Nomenclature
Symbol: Mir122tm1.1Apts
Name: microRNA 122; targeted mutation 1.1, Ann-Ping Tsou
MGI ID: MGI:5448652
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Progressive accumulation of lipid and reduced glycogen storage in Mir122tm1.1Apts/Mir122tm1.1Apts liversMir122tm1.1Apts/Mir122tm1.1Aptsinvolves: 129 * C57BL/6
Increase in the number of Kupffer cells and activation of hepatic stellate cells near the portal regions in Mir122tm1.1Apts/Mir122tm1.1Apts liversMir122tm1.1Apts/Mir122tm1.1Aptsinvolves: 129 * C57BL/6
Liver tumor formation in Mir122tm1.1Apts/Mir122tm1.1Apts malesMir122tm1.1Apts/Mir122tm1.1Aptsinvolves: 129 * C57BL/6
Fatty liver and reduced glycogen storage develops early in Mir122tm1.1Apts/Mir122tm1.1Apts newbornsMir122tm1.1Apts/Mir122tm1.1Aptsinvolves: 129 * C57BL/6
Hepatic fibrosis and inflammation in Mir122tm1.1Apts/Mir122tm1.1Apts femalesMir122tm1.1Apts/Mir122tm1.1Aptsinvolves: 129 * C57BL/6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
MGI 6.23 		The Jackson Laboratory