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Phenotype Images associated with this Allele
Nomenclature
Symbol: Sufub2b273Clo
Name: SUFU negative regulator of hedgehog signaling; Bench to Bassinet Program (B2B/CVDC), mutation 273 Cecilia Lo
MGI ID: MGI:5313712
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
2D serial EFIC image stack of mutant 273-003-NC in the coronal view reveals DORV {SDD}, suboartic VSD, and non-compaction of the ventricular myocardium, bilateral coronary artery fistula
Click thumbnail to play movie.		Sufub2b273Clo/Sufub2b273CloC57BL/6J-Sufub2b273Clo
2D serial EFIC image stack of mutant 273-003-NK in the coronal view reveals muscular VSD and high take-off coronary arteries
Click thumbnail to play movie.		Sufub2b273Clo/Sufub2b273CloC57BL/6J-Sufub2b273Clo
2D serial EFIC image stack of mutant 273-003-NC in the sagittal view reveals DORV
Click thumbnail to play movie.		Sufub2b273Clo/Sufub2b273CloC57BL/6J-Sufub2b273Clo
2D serial EFIC image stack of mutant 273-003-NE in the coronal view reveals perimembranous VSD
Click thumbnail to play movie.		Sufub2b273Clo/Sufub2b273CloC57BL/6J-Sufub2b273Clo
Coronal movie of 273-003-NI obtained from micro-CT scan reveals hydrocephalus, perimembranous VSD, overriding aorta and right duplicated kidney
Click thumbnail to play movie.		Sufub2b273Clo/Sufub2b273CloC57BL/6J-Sufub2b273Clo
2D serial EFIC image stack of mutant 273-003-NI in the coronal view reveals perimembranous VSD and overriding aorta
Click thumbnail to play movie.		Sufub2b273Clo/Sufub2b273CloC57BL/6J-Sufub2b273Clo
Preaxial digit duplication in mutant 273-003-NESufub2b273Clo/Sufub2b273CloC57BL/6J-Sufub2b273Clo
Mutant 273-003-NE with micrognathia and microcephaly with dome shaped head.Sufub2b273Clo/Sufub2b273CloC57BL/6J-Sufub2b273Clo
Hindlimb polydactyly with preaxial digit duplication in mutant 273-003-NISufub2b273Clo/Sufub2b273CloC57BL/6J-Sufub2b273Clo
Microcephaly, micrognathia, and dome shaped head in mutant 273-003-NISufub2b273Clo/Sufub2b273CloC57BL/6J-Sufub2b273Clo
Sufub2b273Clo/Sufub2b273CloC57BL/6J-Sufub2b273Clo
Coronal movie of 273-003-NJ obtained from micro-CT scan reveals cleft palate and hydrocephalus
Click thumbnail to play movie.		Sufub2b273Clo/Sufub2b273CloC57BL/6J-Sufub2b273Clo
Sufub2b273Clo/Sufub2b273CloC57BL/6J-Sufub2b273Clo
Sufub2b273Clo/Sufub2b273CloC57BL/6J-Sufub2b273Clo
Sufub2b273Clo/Sufub2b273CloC57BL/6J-Sufub2b273Clo
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/16/2024
MGI 6.23 		The Jackson Laboratory