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Phenotype Images associated with this Allele
Nomenclature
Symbol: Dctn5b2b315Clo
Name: dynactin 5; Bench to Bassinet Program (B2B/CVDC), mutation 315 Cecilia Lo
MGI ID: MGI:5313698
Synonyms: Nemo
Images for
Allele
Click images for details
Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
2D serial EFIC image stack of 315-002-NB (newborn) in the coronal view reveals overriding aorta, VSD, thin right ventricle and hypoplastic lungs.
Click thumbnail to play movie.		Dctn5b2b315Clo/Dctn5b2b315CloC57BL/6J-Dctn5b2b315Clo
Tubule dilation or mild cystic diseaseDctn5b2b315Clo/Dctn5b2b315CloC57BL/6J-Dctn5b2b315Clo
Tubule dilation or mild cystic diseaseDctn5b2b315Clo/Dctn5b2b315CloC57BL/6J-Dctn5b2b315Clo
Dctn5b2b315Clo/Dctn5b2b315CloC57BL/6J-Dctn5b2b315Clo
Dctn5b2b315Clo/Dctn5b2b315CloC57BL/6J-Dctn5b2b315Clo
Mutant 315-006-NA exhibit micrognathia with severe hypoplasia of the lower jaw.Dctn5b2b315Clo/Dctn5b2b315CloC57BL/6J-Dctn5b2b315Clo
Mutant 315-006-NA show micrognathia with pointy snout and open eyelids.Dctn5b2b315Clo/Dctn5b2b315CloC57BL/6J-Dctn5b2b315Clo
2D serial EFIC image stack of mutant 315-006-NA in the coronal view reveals DORV and subaortic VSD
Click thumbnail to play movie.		Dctn5b2b315Clo/Dctn5b2b315CloC57BL/6J-Dctn5b2b315Clo
Mutant 315-004-2 exhibit cyclopia with anencephaly with no frontonasal process and no oral cavity.Dctn5b2b315Clo/Dctn5b2b315CloC57BL/6J-Dctn5b2b315Clo
Mutant 315-006-NA exhibit malalignment of the great arteries.Dctn5b2b315Clo/Dctn5b2b315CloC57BL/6J-Dctn5b2b315Clo
Mutant 315-007-NA exhibit severe micrognathia and microcephaly with now oral cavity and eyes shifted to the midline.Dctn5b2b315Clo/Dctn5b2b315CloC57BL/6J-Dctn5b2b315Clo
Mutant 315-007-NA exhibit severe micrognathia and microcephaly with no mandible.Dctn5b2b315Clo/Dctn5b2b315CloC57BL/6J-Dctn5b2b315Clo
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory