Phenotype Images associated with this Allele - MGI

About Help FAQ

Phenotype Images associated with this Allele

Nomenclature

Symbol:	Il4ra^tm2Tch
Name:	interleukin 4 receptor, alpha; targeted mutation 2, Talal A Chatila
MGI ID:	MGI:3720593
Synonyms:	IL-4RalphaR576, Il4ra^R576, Q576R

Images for
Allele

Click images for details

Image	Caption	Genotypes involving this allele
Image	Caption	Allelic Composition	Genetic Background
	Lung histology staining of OVA-sensitized control (Q576) and Il4ra^tm2Tch/Il4ra^tm2Tch (R576) mice challenged intranasally with OVA on three consecutive days	Il4ra^tm2Tch/Il4ra^tm2Tch	C.129X1-Il4ra^tm2Tch
	Increased airway inflammation and remodeling in Il4ra^tm2Tch/Il4ra^tm2Tch (R576) mice after chronic allergen challenge	Il4ra^tm2Tch/Il4ra^tm2Tch	C.129X1-Il4ra^tm2Tch
	Increased airway inflammation and remodeling in Il4ra^tm2Tch/Il4ra^tm2Tch (R576) mice after chronic allergen challenge	Il4ra^tm2Tch/Il4ra^tm2Tch	C.129X1-Il4ra^tm2Tch
	Increase in airway hyperreactivity, airway eosinophilia, and goblet cell metaplasia in Il4ra^tm2Tch/Il4ra^tm2Tch mice after IL-13 administration	Il4ra^tm2Tch/Il4ra^tm2Tch	C.129X1-Il4ra^tm2Tch

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/23/2024 MGI 6.23