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Phenotype Images associated with this Allele
Nomenclature
Symbol: Timp4tm1Vuo
Name: tissue inhibitor of metalloproteinase 4; targeted mutation 1, Eero Vuorio
MGI ID: MGI:3663251
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Cardiac rupture, decreased collagen synthesis, and disruption of collagen network in Timp4tm1Vuo/Timp4tm1Vuo hearts after myocardial infarctionTimp4tm1Vuo/Timp4tm1Vuoinvolves: 129S7/SvEvBrd * C57BL/6
Increased neutrophil accumulation in Timp4tm1Vuo/Timp4tm1Vuo hearts at 3 days post-myocardial infarctionTimp4tm1Vuo/Timp4tm1Vuoinvolves: 129S7/SvEvBrd * C57BL/6
Cardiac neutrophil accumulation post-myocardial infraction is normalized in Timp4tm1Vuo/Timp4tm1Vuo Mmp2tm1Ito/Mmp2tm1Ito miceTimp4tm1Vuo/Timp4tm1Vuoinvolves: 129S7/SvEvBrd * C57BL/6
Mmp2tm1Ito/Mmp2tm1Ito
Timp4tm1Vuo/Timp4tm1Vuo		involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory