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Phenotype Images associated with this Allele
Nomenclature
Symbol: Bcl2tm1Dlo
Name: B cell leukemia/lymphoma 2; targeted mutation 1, Dennis Y Loh
MGI ID: MGI:2156165
Synonyms: bcl-2-
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
The Bcl2l11tm3.1Boui mutation ameliorates the degenerative disorders of Bcl2tm1Dlo/Bcl2tm1Dlo miceBcl2tm1Dlo/Bcl2tm1DloB6.129P2-Bcl2tm1Dlo
Bcl2tm1Dlo/Bcl2tm1Dlo
Bcl2l11tm3.1Boui/Bcl2l11tm3.1Boui		B6.Cg-Bcl2tm1Dlo Bcl2l11tm3.1Boui
BH3 replacement mutations in Bcl2l11 prevent the development of polycystic kidney disease and spleen atrophy in Bcl2tm1Dlo/Bcl2tm1Dlo miceBcl2tm1Dlo/Bcl2tm1DloB6.129P2-Bcl2tm1Dlo
Bcl2tm1Dlo/Bcl2tm1Dlo
Bcl2l11tm1.1Boui/Bcl2l11tm1.1Boui		B6.Cg-Bcl2tm1Dlo Bcl2l11tm1.1Boui
Bcl2tm1Dlo/Bcl2tm1Dlo
Bcl2l11tm2.1Boui/Bcl2l11tm2.1Boui		B6.Cg-Bcl2tm1Dlo Bcl2l11tm2.1Boui
Bcl2tm1Dlo/Bcl2tm1Dlo
Bcl2l11tm3.1Boui/Bcl2l11tm3.1Boui		B6.Cg-Bcl2tm1Dlo Bcl2l11tm3.1Boui
Bcl2tm1Dlo/Bcl2tm1Dlo
Bcl2l11tm1.1Boui/Bcl2l11tm2.1Boui		B6.Cg-Bcl2tm1Dlo Bcl2l11tm1.1Boui/Bcl2l11tm2.1Boui
\AlleleSymbol (MGI:2156165|0)/Bcl2tm1Dlo with littermate controlBcl2tm1Dlo/Bcl2tm1Dloinvolves: 129P2/OlaHsd * C57BL/6
Kidney and histological kidney analysisBcl2tm1Dlo/Bcl2tm1Dloinvolves: 129P2/OlaHsd * C57BL/6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory