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Phenotype Images associated with this Allele
Nomenclature
Symbol: Sox10tm1Weg
Name: SRY (sex determining region Y)-box 10; targeted mutation 1, Michael Wegner
MGI ID: MGI:2151173
Synonyms: Sox10-, Sox10lacZ, Sox10LacZKO
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Lack of pigmentation and megacolon in Sox10gt/Sox10tm1Weg pupsSox10gt/Sox10tm1Weginvolves: 129S1/Sv * 129X1/SvJ * GT/Le
Similar distribution and severity of vacuoles in the brain of Sox10gt/Sox10gt and Sox10tm1Weg/Sox10gt miceSox10gt/Sox10gtGT/Le
Sox10gt/Sox10tm1Weginvolves: 129S1/Sv * 129X1/SvJ * GT/Le
Rps7Zma/Rps7+ Sox10tm1Weg/Sox10+ embryos show greatly reduced melanoblast number at E12.5 as compared to E12.5 Sox10tm1Weg/Sox10+ miceRps7Zma/Rps7+
Sox10tm1Weg/Sox10+		involves: 129S1/Sv * 129X1/SvJ * BALB/c * C3H/HeH
Extensive hypopigmentation in Rps7Zma/Rps7+ Sox10tm1Weg/Sox10+ miceRps7Zma/Rps7+
Sox10tm1Weg/Sox10+		involves: 129S1/Sv * 129X1/SvJ * BALB/c * C3H/HeH
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory