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Phenotype Images associated with this Allele
Nomenclature
Symbol: Itgb1tm1Ref
Name: integrin beta 1 (fibronectin receptor beta); targeted mutation 1, Reinhard Fassler
MGI ID: MGI:1926498
Synonyms: beta1fl, beta1 integrin (fl), floxed beta1 integrin
Images for
Allele
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Image Caption Genotypes involving this allele
Allelic Composition Genetic Background
Hair and skin phenotypes of various keratinocyte conditional Itgb1 allelesItgb1tm1Ref/Itgb1tm5.1Ref
Tg(KRT5-cre)5132Jlj/0		involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J
Itgb1tm1Ref/Itgb1tm1Ref
Tg(KRT5-cre)5132Jlj/0		involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J
Itgb1tm1Ref/Itgb1tm12.1Ref
Tg(KRT5-cre)5132Jlj/0		involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J
Defective adhesion and spreading of Itgb1tm1Ref/Itgb1tm12.1Ref Tg(KRT5-cre)5132Jlj/0 primary keratinocytesItgb1tm1Ref/Itgb1tm12.1Ref
Tg(KRT5-cre)5132Jlj/0		involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J
Progressive hair loss in Itgb1tm1Ref/Itgb1tm5.1Ref Tg(KRT5-cre)5132Jlj/0 and Itgb1tm1Ref/Itgb1tm1Ref Tg(KRT5-cre)5132Jlj/0 miceItgb1tm1Ref/Itgb1tm5.1Ref
Tg(KRT5-cre)5132Jlj/0		involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J
Itgb1tm1Ref/Itgb1tm1Ref
Tg(KRT5-cre)5132Jlj/0		involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J
Epidermal and hair follicle abnormalities in Itgb1tm1Ref/Itgb1tm5.1Ref Tg(KRT5-cre)5132Jlj/0 and Itgb1tm1Ref/Itgb1tm1Ref Tg(KRT5-cre)5132Jlj/0 miceItgb1tm1Ref/Itgb1tm5.1Ref
Tg(KRT5-cre)5132Jlj/0		involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J
Itgb1tm1Ref/Itgb1tm1Ref
Tg(KRT5-cre)5132Jlj/0		involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J
Itgb1tm1Ref/Itgb1tm5.1Ref Tg(KRT5-cre)5132Jlj/0 keratinocytes show reduced spreadingItgb1tm1Ref/Itgb1tm5.1Ref
Tg(KRT5-cre)5132Jlj/0		involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA/2J
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory