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| Caption | Malformations of the semicircular canals in Chd7Whi/Chd7+, Tbx1tm1Bld/Tbx1+, and Chd7Whi/Chd7+ Tbx1tm1Bld/Tbx1+ mice. (A) Paint-filled semicircular canals of the right ear of an E16.5 wild-type (WT) mouse showing normal canal morphology. (B) Tbx1tm1Bld/Tbx1+ mouse displaying normal anterior (AC) and posterior canals (PC), but truncation of the lateral canal (arrowhead). (C) Chd7Whi/Chd7+ mouse showing normal morphology of the anterior canal, truncation of the lateral canal, and some shortening of the posterior canal. (D) Chd7Whi/Chd7+ Tbx1tm1Bld/Tbx1+ mouse showing normal anterior canal, fusion of the posterior canal to the crus commune (CC), and absence of the lateral canal. Scale bar: 1 mm. | ||||||||
| Copyright | This image is from Randall V, J Clin Invest 2009 Nov;119(11):3301-10 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:154590 | ||||||||
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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