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Phenotype Image Detail
Image
Caption Comparison of claudin-4 localization pattern in Cldn8tm1.1Jhou/Cldn8tm1.1Jhou Tg(Aqp2-cre)1Dek/0 (CLDN8fl/fl/Aqp2Cre) collecting ducts. Arrows denote remnant claudin-4 tight junction strands in mutant kidneys (where longer exposure time was taken for the claudin-4 signal to be seen).
Copyright This image is from Gong Y, Proc Natl Acad Sci U S A 2015 Apr 7;112(14):4340-5. Copyright 2015 National Academy of Sciences, U.S.A. J:220813
Associated
Alleles
Symbol Name
Cldn8tm1.1Jhou claudin 8; targeted mutation 1.1, Jianghui Hou
Tg(Aqp2-cre)1Dek transgene insertion 1, Donald E Kohan
Associated
Genotypes
Allelic Composition Genetic Background
Cldn8tm1.1Jhou/Cldn8tm1.1Jhou
Tg(Aqp2-cre)1Dek/0
B6.Cg-Cldn8tm1.1Jhou Tg(Aqp2-cre)1Dek

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory