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Phenotype Image Detail
Image
Caption A thin cornea (black arrows in A) and iridocorneal dysgenesis (black arrowheads in B) were observed in the Ext1tm1Yama/Ext1+ H2az2Tg(Wnt1-cre)11Rth/0 Tgfb2tm1Doe/Tgfb2+ mutants at E18.5.
Copyright This image is from Iwao K, J Clin Invest 2009 Jul;119(7):1997-2008 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:152572
Associated
Alleles
Symbol Name
Ext1tm1Yama exostosin glycosyltransferase 1; targeted mutation 1, Yu Yamaguchi
H2az2Tg(Wnt1-cre)11Rth H2A.Z histone variant 2; transgene insertion 11, David H Rowitch
Tgfb2tm1Doe transforming growth factor, beta 2; targeted mutation 1, Thomas Doetschman
Associated
Genotypes
Allelic Composition Genetic Background
Ext1tm1Yama/Ext1+
H2az2Tg(Wnt1-cre)11Rth/H2az2+
Tgfb2tm1Doe/Tgfb2+
B6.Cg-Tgfb2tm1Doe H2az2Tg(Wnt1-cre)11Rth Ext1tm1Yama

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/24/2023
MGI 6.22
The Jackson Laboratory