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Phenotype Image Detail
Image
Caption Exocrine pancreatic insufficiency in Sel1ltm1c(KOMP)Wtsi/Sel1ltm1c(KOMP)Wtsi/ Tg(CAG-cre/Esr1*)5Amc/0 (IKO) mice. Experiments were performed at day 13. (A) Picture of wild-type (WT) and mutant pancreas from male mice. Each picture represents five mice each group. (B) H&E images showing pancreatic atrophy in mutant mice. (C) H&E images showing reduced eosinophilic zymogen staining, different nuclei sizes (arrowheads), and binucleated cells.
Copyright This image is from Sun S, Proc Natl Acad Sci U S A 2014 Feb 4;111(5):E582-91. Copyright 2014 National Academy of Sciences, U.S.A. J:206568
Associated
Alleles
Symbol Name
Sel1ltm1c(KOMP)Wtsi sel-1 suppressor of lin-12-like (C. elegans); targeted mutation 1c, Welcome Trust Sanger Institute
Tg(CAG-cre/Esr1*)5Amc transgene insertion 5, Andrew P McMahon
Associated
Genotypes
Allelic Composition Genetic Background
Sel1ltm1c(KOMP)Wtsi/Sel1ltm1c(KOMP)Wtsi
Tg(CAG-cre/Esr1*)5Amc/0 		involves: C57BL/6 * C57BL/6N * CBA * SJL
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory