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Phenotype Image Detail
Caption Retinal lesion in Ccl2tm1Rol/Ccl2tm1Rol Cx3cr1tm1Litt/Cx3cr1tm1Litt mice. (A-F) Fundus image from 6-month (A), 12-month (B, C), 18-month (D), 10-month+light (E) mutant mice and 18-month wild-type mice (F). Arrows indicate retinal lesions. (G, H) Indocyanine green angiography showing retinal (G) and choroidal (H) circulation of an 18-month old mutant mouse. Choroidal neovascularisation was not observed in mutant mice.
Copyright This image is from Chen M, PLoS One 2013;8(4):e61381, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:200877
Symbol Name
Ccl2tm1Rol chemokine (C-C motif) ligand 2; targeted mutation 1, Barrett J Rollins
Cx3cr1tm1Litt chemokine (C-X3-C motif) receptor 1; targeted mutation 1, Dan R Littman
Allelic Composition Genetic Background
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6J

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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