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| Caption | Abnormal morphology and migration of Slc4a2tm1Ges/Slc4a2tm1Ges (Slc4a2-/-) osteoclasts. (A) Confocal images of F-actin (red) and nuclei (blue) in osteoclast-like cells (OCLs). (Scale bars, 100 um.) (B) Distance moved (means +/- SE) over 5 hours by OCLs (**P < 0.005). (C and D) Transmission electron microscopy (C) and confocal images (D) of osteoclasts at the proximal tibial growth plate from 5-day-old mice. (C) Bone (B), ruffled border (RB), osteoclast (OC), and sealing zone (SZ). (Scale bars, 2 um.) (D) F-actin (red), V-ATPase B2 subunit (green), nuclei (blue) and sealing zones (asterisks). (Scale bars, 5 um.) | ||||
| Copyright | This image is from Coury F, Proc Natl Acad Sci U S A 2013 Feb 5;110(6):2163-8. Copyright 2013 National Academy of Sciences, U.S.A. J:193823 | ||||
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/07/2024 MGI 6.23 |
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