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Phenotype Image Detail
Image
Caption Dlc1Gt(XE082)Byg/Dlc1Gt(XE082)Byg embryos. (i) X-gal stained heterozygous (Dlc1wt/gt) and homozygous (Dlc1gt/gt) mutant embryos and placenta showing expression of Dlc1 exon 1-beta geo fusion protein. (ii) Impairment of yolk sac blood vessel formation in homozygous mutant mouse embryos. The yolk sacs of 10.5 days post coitum (dpc) heterozygous and homozygous mutant mouse embryos with the latter, showing no detectable blood vessels. (iii) Homozygous mutant embryos showing failure to close the neural tube at the anterior part of the body (left: unstained embryos and right: X-gal stained embryos).
Copyright This image is from Sabbir MG, BMC Biol 2010;8():17, an open-access article, licensee BioMed Central Ltd. J:189950
Associated
Alleles
Symbol Name
Dlc1Gt(XE082)Byg deleted in liver cancer 1; gene trap XE082, BayGenomics
Associated
Genotypes
Allelic Composition Genetic Background
Dlc1Gt(XE082)Byg/Dlc1Gt(XE082)Byg involves: 129P2/OlaHsd * C57BL/6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory