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| Caption | (A and B) Representative hematoxylin and eosin-stained (H&E) kidney sections showing infiltration of leukocytes (arrow) around the renal cortical vessels in 100% of Slc26a1tm1Mark/Slc26a1tm1Mark (Sat1-/-) mice (n = 8), absent in wild-type (Sat1+/+) mice. (C-F) Representative Yasue-stained kidney (C and D) and bladder (E and F) sections showing calcium oxalate stones (dark staining) in kidney tubules of 47% mutant mice (n = 15) and bladders of 26% mutant mice (n = 19), but not in any wild-type mice (n = 10). Gross histological analyses of additional tissues in which Slc26a1 is expressed (liver and brain) showed no structural differences between mutant and wild-type mice (not shown). Scale bars: 100 um (A and B); 500 um (C and D); 2 mm (E and F). | ||||
| Copyright | This image is from Dawson PA, J Clin Invest 2010 Mar;120(3):706-12 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:158567 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/07/2024 MGI 6.23 |
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