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Phenotype Image Detail
Image
Caption Liver architecture and lung morphology are distorted in Cebpatm1Kgx/Cebpatm1Kgx mice. A representative series of histologic sections of liver and lung tissues stained with hematoxylin and eosin. Note the acinar formation in the livers of Cebpatm1Kgx/Cebpatm1Kgx (-/-) mutants. Pulmonary histology of newborn littermates indicates hyperproliferation of type II pneumocytes in mutant mice and results in reduction in the alveolar airsapce (arrow, middle right panel) and interstitial thickening (arrow, lower right panel).
Copyright This image is from Flodby P, J Biol Chem 1996 Oct 4;271(40):24753-60 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:35795
Associated
Alleles
Symbol Name
Cebpatm1Kgx CCAAT/enhancer binding protein alpha; targeted mutation 1, Kleanthis G Xanthopoulos
Associated
Genotypes
Allelic Composition Genetic Background
Cebpatm1Kgx/Cebpatm1Kgx involves: 129S1/Sv * 129X1/SvJ * C57BL/6

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory