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| Caption | Frozen sections of the kidneys isolated from wild-type (A) and Lgmntm1Ihn/Lgmntm1Ihn (B) mice were subjected to immunofluorescent microscopy with anti-lamp-2 antibody. Arrowheads indicate enlarged structures found in the mutant mice. Asterisks mark the lumen of proximal tubule. Bars=5 um. C and D: Electron microscopic images of the proximal tubule cells of mutant mice. Arrowheads indicate the large and aberrant lysosomes containing electron-dense and/or membranous materials. BB, brush border; BL, basal lamina; Mt, mitochondrion. Bars = 1 um. | ||||
| Copyright | This image is from Shirahama-Noda K, J Biol Chem 2003 Aug 29;278(35):33194-9 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:85207 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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