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| Caption | Cardiac structural analyses of Tg(Myh6-Myl2*)21Rbns/0 mice. A: Typical whole mounts of intact hearts derived from a non-transgenic (NTG) and lines 42, 35 and 21. The hearts shown are representative of multiple hearts, which have been examined from each line. Note the significant increase in atrial size in hearts derived from lines 21 and 35. These hearts typically showed biatrial dilation and dilated right ventricles. In some cases, organized atrial thrombi were also found. B and C, shown are hematoxolyin and eosin stained sections derived from left ventricle (LV) free walls of NTG (B) and mutant (C) hearts (line 21). When compared with the NTG-derived section, the mutant material shows mild ventricular myocyte abnormalities. Line 35 showed an identical phenotype, while line 42 appeared normal. All hearts were derived from 3-4 month old males. | ||||
| Copyright | This image is from Sanbe A, J Biol Chem 1999 Jul 23;274(30):21085-94 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:114298 | ||||
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Associated Alleles |
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Associated Genotypes |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/07/2024 MGI 6.23 |
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