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Image
Caption Histology of the bone marrow (BM) microenvironment of nonirradiated Ptpn2tm1Mtr/Ptpn2tm1Mtr mice. Analysis of BM was performed on 21 day old mice. A: Stromal cells (arrrows) are attached to, or clustered between bone trabeculae in control mice. B: By contrast, a marked paucity of stromal cells is observed in the BM of mutant mice in those areas normally rich in stromal cells. The hematopoietic cell population is comparable in both groups of mice. Periodic-acid Schiff stain; original magnification: x150.
Copyright This image is from You-Ten KE, J Exp Med 1997 Aug 29;186(5):683-93, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:42595
Associated
Alleles
Symbol Name
Ptpn2tm1Mtr protein tyrosine phosphatase, non-receptor type 2; targeted mutation 1, Michel L Tremblay
Associated
Genotypes
Allelic Composition Genetic Background
Ptpn2tm1Mtr/Ptpn2tm1Mtr involves: 129S4/SvJae * BALB/c

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory