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Phenotype Image Detail
Image
Caption C: Foxp2tm1Momo/Foxp2tm1Momo mice (Homo, right) at P10 are about 30% smaller and Foxp2tm1Momo/Foxp2+ mice (center) are about 10-15% smaller than wild type (left) mice. D: Brains of wild type (left), heterozygous (center), and homozygous mutant (right) mice at P10. Arrows indicate the cerebella. The size of the homozygous mutant cerebellum is smaller than the wild type and heterozygous ones. E: Hematoxylin and eosin stainng of the cerebella at P4 and P19. The development of folia of the homozygous mutant cerebellum was morphologically immature with less folia that were incompletely folded.
Copyright This image is from Fujita E, Proc Natl Acad Sci U S A 2008 Feb 26;105(8):3117-22. Copyright 2008 National Academy of Sciences, U.S.A. J:132813
Associated
Alleles
Symbol Name
Foxp2tm1Momo forkhead box P2; targeted mutation 1, Takashi Momoi
Associated
Genotypes
Allelic Composition Genetic Background
Foxp2tm1Momo/Foxp2tm1Momo involves: 129S6/SvEvTac * C57BL/6
Foxp2tm1Momo/Foxp2+ involves: 129S6/SvEvTac * C57BL/6

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
06/12/2024
MGI 6.13
The Jackson Laboratory