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| Caption | Targeted disruption of the Slc32a1 gene generating the Slc32a1tm1.1Bgc allele. (A) A schematic representation of the Slc32a1 wild-type genomic locus (Genomic Structure), the targeting vector (Targeting Construct), and the mutant locus (Targeted structure) are shown. A LacZ sequence was inserted into an NcoI site at the start codon. The lox sites that flank the Neo resistance cassette are indicated with two arrowheads in the region immediately 3' to the lacZ sequence. The locations ofthe 5' (5' Probe) and 3' (3' Probe) flanking probes used in characterizing the allele are indicated above the map of the wild-type locus. The positions of the restriction sites used in the Southern blot analysis of genomic DNA from ES cells are indicated by single letters. Restriction sites are indicated as follows: H (HindIII), Nc (NcoI), A (Asp718) and N (NotI). | ||||
| Copyright | This image is from Oh WJ, PLoS One 2010;5(3):e9758, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:158888 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 05/07/2024 MGI 6.23 |
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