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Molecular Image Detail
Image
Caption Generation of Gja10tm2(Hbegf/EGFP)Kwi A. Part of exon 2 was replaced by the HBEGF/EGFP fusion construct flanked by frt (DTRfrtCre) sites, and the NLS-Cre recombinase sequence and followed by a neomycin resistance marker (neoR). DTR-eGFP: diphtheria toxin receptor (DTR; HBEGF) and EGFP fusion protein; NLS: nuclear localization signal. B. Southern blot analysis. 7.2 kb band confirms correct targeting of cre construct to the Gja10 (Cx57) locus. Successful Flp-mediated excision of DTR produces 8.7 kb band.
Copyright This image is from Stroh S, PLoS One 2013;8(12):e83076, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:207456
Associated
Alleles
Symbol Name
Gja10tm2(Hbegf/EGFP)Kwi gap junction protein, alpha 10; targeted mutation 2, Klaus Willecke

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory