About   Help   FAQ
Molecular Image Detail
Image
Caption C) The third exon of CARM1 (*) harbors a critical arginine residue (Arg169) that was mutated to an alanine in the original knock-out construct to generate a knock-in construct. Heterozygous mice were crossed with a Flp recombinase-expressing mouse to remove the Neo cassette and generate the Carm1tm2.1Mtb allele. Arrowheads depict loxP sites; solid boxes depict exons; and gray boxes depict frt sites. The position of the external Southern probe is noted.
Copyright This image is from Kim D, J Biol Chem 2010 Jan 8;285(2):1147-52 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:159958
Associated
Alleles
Symbol Name
Carm1tm2.1Mtb coactivator-associated arginine methyltransferase 1; targeted mutation 2.1, Mark T Bedford

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/07/2024
MGI 6.23
The Jackson Laboratory