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Molecular Image Detail
Image
Caption A, schematic representation of the targeting vector for the generation of the Thtm1.1Ich (floxed Th allele) allele. E, EcoRI; H, HindIII; M, Mlul; N, NotI; S, Spel; X, Xhol; Neo, neomycin-resistant cassette. Broken arrows represent the generation or replacement of a restriction site. Exons are represented by boxes. The positions of the primers designed for the detection of genomic DNA recombination by PCR are indicated by open triangles with resulting PCR product sizes. Cre-mediated recombination results in the removal of the floxed region and generates a deleted Th allele.
Copyright This image is from Tokuoka H, J Biol Chem 2011 Dec 16;286(50):43549-58 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:178698
Associated
Alleles
Symbol Name
Thtm1.1Ich tyrosine hydroxylase; targeted mutation 1.1, Hiroshi Ichinose

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory