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| Caption | (A) Targeting strategy to knockout Htra1 from mouse. Structures of Htra1 gene, targeting vector, and targeted mutant locus are shown. Blue boxes represent exons of mouse Htra1. Part of exon 1, including ATG initiation codon, was replaced with an IRES-lacZ reporter and neomycin-resistance cassette (IRES-lacZ-neo) to create the Htra1tm1Ybf allele. B, BamHI. E, EcoRI. SV polyA, SV40 polyadenylation signal. | ||||
| Copyright | This image is from Jones A, Proc Natl Acad Sci U S A 2011 Aug 30;108(35):14578-83. Copyright 2011 National Academy of Sciences, U.S.A. J:175227 | ||||
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Associated Alleles |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/23/2024 MGI 6.23 |
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