Phenotype Image Detail

Image

Caption

Stt3b^em1(IMPC)J/Stt3b^em1(IMPC)J (Stt3b-/-) embryonic phenotype. Stt3b-/- embryos are normal at E8.5. By E9.5 almost all Stt3b-/- embryos have completed turning, are often small but within the expected range and occasionally display cardiac or pericardial edema, but the majority remain otherwise indistinguishable from control littermates. By E10.5 many Stt3b-/- embryos are delayed and all display abnormal heart morphology that includes cardiac and/or pericardial edema, abnormal yolk sac morphology, abnormal head shape and abnormal branchial arches. All E11.5 Stt3b mutants recovered are dying or resorbing.

Copyright

This image was contributed directly to MGI. Questions regarding this image or these data should be directed to Dr. Kimberly D. Tremblay at kdtrembl@umass.edu. J:374598

Associated Alleles

Symbol	Name
Stt3b^em1(IMPC)J	STT3, subunit of the oligosaccharyltransferase complex, homolog B (S. cerevisiae); endonuclease-mediated mutation 1, Jackson

Associated Genotypes

Allelic Composition	Genetic Background
Stt3b^em1(IMPC)J/Stt3b^em1(IMPC)J	C57BL/6NJ-Stt3b^em1(IMPC)J/Mmjax