Gene Expression Image Detail

Reference

Figure

ID

J:171050 Thiagarajan RD, et al., PLoS One. 2011;6(2):e17286

5

MGI:7840107

Image

Caption

A) Expression patterns determined by section in situ hybridization at 15.5dpc were painted onto a schematic of stage III and IV nephrons. early proximal tubule (EPT), loop of Henle (LOH) compartments of the nephron. Both tubular and renal corpuscle (RC) structures were painted and expression strength is indicated by colour. Expression in the adult nephron is indicated in text on the right of each schematic (renal proximal tubule S1 S2 S3 segments, DCT distal convoluted tubule, DST distal straight tubule and LOH) and (-) indicates expression is absent. Unknown = expression was not examined, ? = uncertain expression. Red (*) indicates that these EPT genes also showed expression in a subset of the distal tubules in the adult kidney. EPT genes with restricted expression in the nephron tubules were divided into 3 categories; (A) early genes showing expression in Stage III and IV tubules, (B) late genes restricted to EPT of Stage IV tubules, the EPT anchor genes and (C) late genes with expression in EPT and other tubular segments (immature loop of Henle and/or early distal tubule). (D) EPT genes which showed additional expression in the renal corpuscle nephron compartment represent an additional category of enriched EPT genes. (A'-D') Expression patterns in the kidney at 15.5dpc by section in situ hybridization. In C', arrowheads indicate expression in immature LOH. Images and text-annotated expression patterns for all genes are available on the GUDMAP website (http://www.gudmap.org).

Copyright

This image is from Thiagarajan RD, PLoS One 2011;6(2):e17286, and is displayed under the terms of the Creative Commons Attribution License.

Associated
Assays

Label	Assay & Result Details (Gene Symbol)	Spatial Mapping
A' Aadac	MGI:7840458 (Aadac)
A' Hdc	MGI:7850609 (Hdc)
A' Myo15b	MGI:7850610 (Myo15b)
B' Fbp1	MGI:7840378 (Fbp1)
B' Slc27a2	MGI:7840419 (Slc27a2)
B' Ugtb37	MGI:7840426 (Ugt2b37)
B' Cml1	MGI:7840413 (Nat8f1)
B' Slc3a1	MGI:7840420 (Slc3a1)
B' Sord	MGI:7840422 (Sord)
C' Serpina10	MGI:7850613 (Serpina10)
C' Slc23a1	MGI:7850615 (Slc23a1)
C' Gyk	MGI:7850607 (Gk)
D' Gpd1	MGI:7850608 (Gpd1)
D' Susd2	MGI:7850618 (Susd2)
D' Dpep1	MGI:7850594 (Dpep1)