Gene Expression Image Detail

Reference

Figure

ID

J:276901 Taroc EZM, et al., Front Cell Neurosci. 2019;13:70

1

MGI:6511053

Image

Caption

(A) Schematic representing the head of an E15 mouse embryo. The olfactory epithelium and vomeronasal organ are represented in blue in the nasal area. The GnRH-1 neurons (yellow dots) originating from the VNO are shown on their migratory route, indicated by purple dotted lines and arrows. The GnRH-1 neurons enter the brain (gray) at the level of the forebrain junction where a small number of cells migrate around the olfactory bulb while the majority of cells migrate to the pre-optic area of the hypothalamus. (B) In situ hybridization at E14.5. (C) Magnification of boxed area in (B). (D) E14.5 immunostaining in Robo3-EGFP/+ knock in mouse embryo. Nuclei are stained in blue. (E1-3) Arrowheads indicate the Robo3-EGFP-positive fibers of the putative terminal nerve. Arrows indicate double-labeled cells, see single channels in (D2,3). Scale bars are 500 um in (B), 250 um in (C), and 200 um in (D1-E3). Abbreviations: cortex (Ctx); forebrain junction (FBJ); olfactory bulb (OB); olfactory ensheathing cells (OECs); olfactory epithelium (OE); pre-optic area (POA); ventral anterior olfactory nucleus (vAON); vomeronasal organ (VNO).

Copyright

This image is from Taroc EZM, Front Cell Neurosci 2019;13():70, and is displayed under the terms of the Creative Commons Attribution 4.0 International License.

Associated
Assays

Label	Assay & Result Details (Gene Symbol)	Spatial Mapping
B	MGI:6511299 (Nell2)
C	MGI:6511299 (Nell2)
D1	MGI:6511320 (Gnrh1) MGI:6511319 (Robo3)
D2	MGI:6511320 (Gnrh1)
D3	MGI:6511319 (Robo3)
E1	MGI:6511320 (Gnrh1) MGI:6511319 (Robo3)
E2	MGI:6511320 (Gnrh1)
E3	MGI:6511319 (Robo3)