Phenotype Image Detail

Image

Caption

Absence of melanocytes or pigment in hair follicles of Yy1^tm2.1Yshi/Yy1^tm2.1Yshi Tg(Tyr-cre)1Lru/Y Tg(Dct-lacZ)A12Jkn/0 mice at the anagen phase of the second hair cycle. XGal stain of whole-mount skin sections from P38 Tg(Tyr-cre)1Lru/Y Yy1^tm2.1Yshi/Yy1⁺ Tg(Dct-lacZ)A12Jkn/0 (TyrCre, yy1^f/+) (K) and Tg(Tyr-cre)1Lru/Y Yy1^tm2.1Yshi/Yy1^tm2.1Yshi Tg(Dct-lacZ)A12Jkn/0 (TyrCre, yy1^f/f) (L) mice.

Copyright

This image is from Li J, PLoS Genet 2012 May;8(5):e1002688, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:185128

Associated Alleles

Symbol	Name
Tg(Dct-lacZ)A12Jkn	transgene insertion A12, Ian Jackson
Tg(Tyr-cre)1Lru	transgene insertion 1, Lionel Larue
Yy1^tm2.1Yshi	YY1 transcription factor; targeted mutation 2.1, Yang Shi

Associated Genotypes

Allelic Composition	Genetic Background
Yy1^tm2.1Yshi/Yy1^tm2.1Yshi Tg(Dct-lacZ)A12Jkn/0 Tg(Tyr-cre)1Lru/Y	involves: 129S4/SvJae * C57BL/6 * CBA * DBA/2