Gene Expression Image Detail

Reference

Figure

ID

J:237110 Lee YG, et al., Dev Dyn. 2016 Dec;245(12):1189-1197

2

MGI:6196885

Image

Caption

A-F: Whole-mount immunostaining at E12.5. Arrows indicate direction of migrating lymphatic endothelial cells from the region where forelimbs are attached to the body (B,E, white dotted line). Scale bars, 500 um. G: Developing inguinal lymph node sites were immunostained. Scale bars, 200 um. H: Double immunostaining for proliferative lymphatic endothelial cells (white arrowheads) at E14.5. Scale bars, 50 um. I: The size of CD4 lymphoid inducer cell clusters (dotted lines) were compared between the wild-type and Vegfc^+/LacZ littermates at E14.5. Scale bars, 200um. Abbreviations: FL, forelimb; HL, hindlimb. J: Stereoscopic images of Vegfc^+/LacZ embryos after whole-mount X-gal staining. White arrow indicates lymphedema. Inguinal lymph node anlagen sites are positive for VEGF-C expression (white arrowheads, insets at higher magnification).

Copyright

This image is from Lee YG, Dev Dyn 2016 Dec;245(12):1189-1197 and is displayed with the permission of Wiley-Blackwell, who owns the Copyright.

Associated
Assays

Label	Assay & Result Details (Gene Symbol)	Spatial Mapping
A	MGI:6196899 (Pecam1) MGI:6197042 (Prox1)
B	MGI:6196899 (Pecam1) MGI:6197042 (Prox1)
C	MGI:6196899 (Pecam1) MGI:6197042 (Prox1)
D	MGI:6196899 (Pecam1) MGI:6197042 (Prox1)
E	MGI:6196899 (Pecam1) MGI:6197042 (Prox1)
F	MGI:6196899 (Pecam1) MGI:6197042 (Prox1)
G E12.5 Vegfc+/+	MGI:6196899 (Pecam1) MGI:6197042 (Prox1)
G E12.5 Vegfc+/LacZ	MGI:6196899 (Pecam1) MGI:6197042 (Prox1)
G E14.5 Vegfc+/+	MGI:6196899 (Pecam1) MGI:6197042 (Prox1)
G E14.5 Vegfc+/LacZ	MGI:6196899 (Pecam1) MGI:6197042 (Prox1)
H Vegfc+/+	MGI:6197047 (Mki67) MGI:6197042 (Prox1)
H Vegfc+/LacZ	MGI:6197047 (Mki67) MGI:6197042 (Prox1)
I Vegfc+/+	MGI:6197052 (Cd4) MGI:6197053 (Pecam1)
I Vegfc+/LacZ	MGI:6197052 (Cd4) MGI:6197053 (Pecam1)
J E12.5	MGI:6197054 (Vegfc)
J E14.5	MGI:6197054 (Vegfc)