Phenotype Image Detail

Image

Caption

Heart sections of 15-day (upper pair), 25-day (middle pair) and 29-day old (lower pair) Med1^tm2Jkr/Med1^tm2Jkr Tg(Myh6-cre)2182Mds/0 (csMed1^-/-) heart stained with H&E reveal thinning of ventricular walls and dilation of chambers.

Copyright

This image is from Jia Y, PLoS One 2016;11(8):e0160755, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:243730

Associated Alleles

Symbol	Name
Med1^tm2Jkr	mediator complex subunit 1; targeted mutation 2, Janardan K Reddy

Associated Genotypes

Allelic Composition	Genetic Background
Med1^tm2Jkr/Med1^tm2Jkr Tg(Myh6-cre)2182Mds/0	involves: 129P2/OlaHsd * FVB/N