Phenotype Image Detail

Image

Caption

Coronary plexus in Zfpm2^tm1Sho/Zfpm2^tm2Sho Nkx2-5^tm1(cre)Rjs/Nkx2-5⁺ (Fog2^NK) and littermate controls. (A) PECAM wholemount staining of two control genotypes. (B) Section of PECAM wholemount stained hearts demonstrating a paucity of coronary vessels in mutant compared with littermate control. The boundaries of the compact myocardium are indicated by red lines. Bar = 200 um.

Copyright

This image is from Zhou B, J Clin Invest 2009 Jun;119(6):1462-76 and is displayed with the permission of the American Society for Clinical Investigation who owns the Copyright. J:150452

Associated Alleles

Symbol	Name
Nkx2-5^tm1(cre)Rjs	NK2 homeobox 5; targeted mutation 1, Robert J Schwartz
Zfpm2^tm1Sho	zinc finger protein, multitype 2; targeted mutation 1, Stuart Orkin
Zfpm2^tm2Sho	zinc finger protein, multitype 2; targeted mutation 2, Stuart Orkin

Associated Genotypes

Allelic Composition	Genetic Background
Zfpm2^tm1Sho/Zfpm2^tm2Sho Nkx2-5^tm1(cre)Rjs/Nkx2-5^+	involves: 129S1/Sv * 129S7/SvEvBrd