Phenotype Image Detail

Image

Caption

Kalrn^tm2.1Npl/Kalrn^tm2.1Npl (KalSR^KO/KO) mice have abnormal skeletal muscle ultrastructure. Diaphragm muscle from wild-type (WT) and mutant male and female mice was prepared for electron microscopic analysis. Representative images showing alterations in muscle (A, B) and neuromuscular junction (C, D) architecture are shown. A sarcomere, with the A, I and Z bands marked, is shown in (A).

Copyright

This image is from Mandela P, BMC Neurosci 2012;13():136, an open-access article, licensee BioMed Central Ltd. J:206512

Associated Alleles

Symbol	Name
Kalrn^tm2.1Npl	kalirin, RhoGEF kinase; targeted mutation 2.1, Neuropeptide Laboratory

Associated Genotypes

Allelic Composition	Genetic Background
Kalrn^tm2.1Npl/Kalrn^tm2.1Npl	B6.Cg-Kalrn^tm2.1Npl