Phenotype Image Detail

Image

Caption

Accumulation of vacuoles in Pik3c3^tm1Tssk/Pik3c3^tm1Tssk Tg(Cryaa-cre)10Mlr/0 secondary lens fiber cells. A, electron micrographs of fiber cells in the cortical region of the lens in 0.5-day-old Pik3c3^tm1Tssk/Pik3c3^tm1Tssk Tg(Cryaa-cre)10Mlr/0 (Pik3c3^flox/flox;Tg(Cryaa-cre)10Mlr/0) and Pik3c3^tm1Tssk/Pik3c3⁺ Tg(Cryaa-cre)10Mlr/0 (Pik3c3^flox/+;MLR10-Cre) mice. Magnified images in the indicated regions are shown in the right panels. Scale bars, 10 um (left) and 1 um (right).

This image is from Morishita H, J Biol Chem 2013 Apr 19;288(16):11436-47 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:198392

Associated
Alleles

Symbol	Name
Pik3c3^tm1Tssk	phosphatidylinositol 3-kinase catalytic subunit type 3; targeted mutation 1, Takehiko Sasaki
Tg(Cryaa-cre)10Mlr	transgene insertion 10, Mike Robinson

Associated
Genotypes

Allelic Composition	Genetic Background
Pik3c3^tm1Tssk/Pik3c3^tm1Tssk Tg(Cryaa-cre)10Mlr/0	involves: FVB/N

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