Phenotype Image Detail

Image

Caption

Significant decrease of M opsin expression in the retina of Mirc35hg^{Gt(D016D06)Wrst}/Mirc35hg^{Gt(D016D06)Wrst} (miR-183C^GT/GT) mice. Peanut agglutinin (PNA) staining and co-immunofluorescence (IF) of whole mount retina (A) and retinal sections (B and C) of 5-week- (A and B) and 1-year-old (C) mutant mice and their wild-type (miR-183C+/+) littermate controls. The histograms at the bottom of A show the number of M opsin-positive (M opsin+) cones, the total number of cones per square micrometer, and the percentage of total cones that were M opsin positive in the superior (sup.) and inferior (inf.) retina.

Copyright

This image is from Lumayag S, Proc Natl Acad Sci U S A 2013 Feb 5;110(6):E507-16. Copyright 2013 National Academy of Sciences, U.S.A. J:193822

Associated Alleles

Symbol	Name
Mirc35hg^Gt(D016D06)Wrst	microRNA cluster 35, host gene; gene trap D016D06, German Gene Trap Consortium

Associated Genotypes

Allelic Composition	Genetic Background
Mirc35hg^Gt(D016D06)Wrst/Mirc35hg^Gt(D016D06)Wrst	involves: 129S2/SvPas * C57BL/6J