Phenotype Image Detail

Image

Caption

Placental hypotrophy and insufficiency in Ptp4a2^{Gt(AQ0673)Wtsi}/Ptp4a2^{Gt(AQ0673)Wtsi} (PRL2-/-) mice. D-K, histological examination of wild-type and mutant placentas at E16.5. D and E, H&E staining at 2X. F and G, H&E staining at 100X. Arrows designate islands of glycogen cells. H and I, in situ hybridization using Tpbp probe marking spongiotrophoblast cells (dark blue) and glycogen cells (light blue). J and K, PAS staining for glycogen-containing cells (pink signal). Arrows designate islands of glycogen cells. De, deciduas; Sp, spongiotrophoblast; La, labyrinth.

Copyright

This image is from Dong Y, J Biol Chem 2012 Sep 14;287(38):32172-9 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:190411

Associated Alleles

Symbol	Name
Ptp4a2^Gt(AQ0673)Wtsi	protein tyrosine phosphatase 4a2; gene trap AQ0673, Wellcome Trust Sanger Institute

Associated Genotypes

Allelic Composition	Genetic Background
Ptp4a2^Gt(AQ0673)Wtsi/Ptp4a2^Gt(AQ0673)Wtsi	involves: 129P2/OlaHsd * C57BL/6
Ptp4a2^Gt(AQ0673)Wtsi/Ptp4a2^Gt(AQ0673)Wtsi Tg(CAG-Ptp4a2,-EGFP)11Zyz/0	involves: 129P2/OlaHsd * C57BL/6 * FVB/N