Gene Expression Image Detail

Reference

Figure

ID

J:85580 Fedtsova N, et al., Dev Biol. 2003 Sep 15;261(2):456-69

8

MGI:5501139

Image

Caption

(A) Diagram of an E8.5 mouse embryo showing the approximate level of the transverse sections appearing in wild-type (B) and Shh knockout (C) mice. Scale bar: 50 um. (D-G) Trigeminal morphology in E10.5 wild-type and Shh null embryos. Whole-mount views in (D, F) show the level of the coronal sections used for immunofluorescence. Scale bar: 200 um. (H-J) Morphology of the dorsal root ganglia in control (H) and Shh null (I, J) embryos. In serial sections from the forelimb level of a single embryo, DRG neurons were observed to condense variably in bilateral positions or at the ventral midline (arrows). Nonnuclear staining for Islet in these sections is an artifact due to cross-reactivity of the secondary anti-mouse IgG antibody with endogenous mouse antigens. Scale bar: 100 um. Abbreviations: 5g, trigeminal ganglion; drg, dorsal root ganglion; fp, floor plate; SC, spinal cord.

Copyright

Reprinted with permission from Elsevier from 10.1016/S0012-1606(03)00316-6 Dev Biol 261: 456-69, Fedtsova N; Perris R; Turner EE, Sonic hedgehog regulates the position of the trigeminal ganglia. Copyright 2003

Associated
Assays

Label	Assay & Result Details (Gene Symbol)	Spatial Mapping
B	MGI:5501143 (Pax3)
C	MGI:5501143 (Pax3)
E	MGI:5501146 (Isl1) MGI:5501148 (Isl2) MGI:5501145 (Pou4f1)
G	MGI:5501146 (Isl1) MGI:5501148 (Isl2) MGI:5501145 (Pou4f1)
H	MGI:5501146 (Isl1) MGI:5501148 (Isl2) MGI:5501145 (Pou4f1)
I	MGI:5501146 (Isl1) MGI:5501148 (Isl2) MGI:5501145 (Pou4f1)
J	MGI:5501146 (Isl1) MGI:5501148 (Isl2) MGI:5501145 (Pou4f1)