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Gene Expression Data
Assay Details
Assay
Reference: J:85580 Fedtsova N, et al., Sonic hedgehog regulates the position of the trigeminal ganglia. Dev Biol. 2003 Sep 15;261(2):456-69
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5501146
Gene symbol: Isl1
Gene name: ISL1 transcription factor, LIM/homeodomain
Antibody: clone 40.2D6
Detection system: Secondary antibody coupled to Alexa Fluor 594
Assay notes: Antibody recognizes Isl1 and Isl2; both were annotated.
Results
Specimen 8E: embryonic day 10.5 (more )
Note: Double labeled: red - Isl1 and Isl2; green - Pou4f1 (Brn3a; assay MGI:5501145).
Structure Level Pattern Image Note
TS17: trigeminal ganglion Present 8E
Specimen 8G: embryonic day 10.5; Shhtm1Chg/Shhtm1Chg (more )
Note: Double labeled: red - Isl1 and Isl2; green - Pou4f1 (Brn3a; assay MGI:5501145).
Structure Level Pattern Image Note
TS17: trigeminal ganglion Present 8G Expression was detected in the abnormal single ganglion that forms in the mutant.
Specimen 8H: embryonic day 11.5 (more )
Note: Double labeled: red - Isl1 and Isl2; green - Pou4f1 (Brn3a; assay MGI:5501145).
Structure Level Pattern Image Note
TS19: dorsal root ganglion Present 8H
Specimen 8I: embryonic day 11.5; Shhtm1Chg/Shhtm1Chg (more )
Note: Double labeled: red - Isl1 and Isl2; green - Pou4f1 (Brn3a; assay MGI:5501145).
Structure Level Pattern Image Note
TS19: dorsal root ganglion Present 8I Expression was detected in the abnormal dorsal root ganglion cells in the mutant.
Specimen 8J: embryonic day 11.5; Shhtm1Chg/Shhtm1Chg (more )
Note: Double labeled: red - Isl1 and Isl2; green - Pou4f1 (Brn3a; assay MGI:5501145).
Structure Level Pattern Image Note
TS19: dorsal root ganglion Present 8J Expression was detected in the abnormal dorsal root ganglion cells in the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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