Gene Expression Image Detail

Reference

Figure

ID

J:145849 Wu X, et al., Gene Expr Patterns. 2009 Apr;9(4):224-30

2

MGI:5449381

Image

Caption

(A) Bmp7 lacZ/+ embryo stained with X-gal, left hindlimb is removed, area of sections is shown in a frame. (B) Schematic depiction of the cloacal area at E12.5 showing the genital tubercle (GT), cloaca (cl), urorectal septum (urs), urogenital sinus (ugs), hindgut (hg), peritoneal cavity (pc), and the tail (tl). Arrows indicate planes of transverse sections in (F-H, J-L). (C) Ventral view of X-gal stained Bmp7 lacZ/+ and Bmp7 lacZ/lacZ. Urethral plate (up); urethral epithelium (ue). (E,I) Sagittal sections of heterozygous (E) and null (I) embryos. Ventral ectoderm (ve); kidney (k). (F-H, J-L) Transverse sections of heterozygous (F-H) and null (J-L) embryos. Genital mesenchyme (gm). Red arrows in H,L indicate ventral extension of the urethral plate measured in D. Asterisks in K,L insets indicate points of contact between the urethral plate and ventral ectoderm in the null. Scale bar: 100 mm.

Copyright

Reprinted with permission from Elsevier from 10.1016/j.gep.2008.12.005 Gene Expr Patterns 9: 224-30, Wu X; Ferrara C; Shapiro E; Grishina I, Bmp7 expression and null phenotype in the urogenital system suggest a role in re-organization of the urethral epithelium. Copyright 2009

Associated
Assays

Label	Assay & Result Details (Gene Symbol)	Spatial Mapping
A	MGI:5449354 (Bmp7)
C +/-	MGI:5449354 (Bmp7)
C -/-	MGI:5449354 (Bmp7)
E	MGI:5449354 (Bmp7)
F	MGI:5449354 (Bmp7)
G	MGI:5449354 (Bmp7)
H	MGI:5449354 (Bmp7)
I	MGI:5449354 (Bmp7)
J	MGI:5449354 (Bmp7)
K	MGI:5449354 (Bmp7)
L	MGI:5449354 (Bmp7)