Phenotype Image Detail

Image

Caption

Histopathology of mouse hearts. A, sections of 18-month-old wild-type (WT), Tnni3^tm1.1Jdp/Tnni3⁺ (R21C+/-), and Tnni3^tm1.1Jdp/Tnni3^tm1.1Jdp (R21C+/+) hearts showing hypertrophy of the left ventricle and septal wall in Tnni3^tm1.1Jdp/Tnni3^tm1.1Jdp mice. B, cross-sections of the left ventricle stained with Masson trichrome showing interstitial fibrosis and myofibrilar disarray in Tnni3^tm1.1Jdp/Tnni3^tm1.1Jdp mice (bars=100 um).

Copyright

This image is from Wang Y, J Biol Chem 2012 Jan 13;287(3):2156-67 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:180606

Associated Alleles

Symbol	Name
Tnni3^tm1.1Jdp	troponin I, cardiac 3; targeted mutation 1.1, James Potter

Associated Genotypes

Allelic Composition	Genetic Background
Tnni3^tm1.1Jdp/Tnni3^tm1.1Jdp	involves: 129S6/SvEvTac * C57BL/6