Gene Expression Image Detail

Reference

Figure

ID

J:142567 Capellini TD, et al., Genesis. 2008 Nov;46(11):683-96

6

MGI:5295065

Image

Caption

Developing notochord (red insets and black arrowheads). (a') All sections shown are at the lumbar-sacral level, except for the E13.5 section shown for Leprel2, which is more caudal (ca). Leprecan was expressed in the neural arches (black arrow) and laminae (red arrow) of the developing vertebrae, at E10.5 and E13.5 Leprel1 was expressed in the neural tube (black arrows), and at E11.5-E12.5, Leprel2 was expressed in the dorsal root ganglia (black arrows) and floor-plate (red arrow). (b') Additional domains of expression are revealed by sections at varying axial levels. Leprecan was expressed in the developing forelimb (a, d, black arrowheads), hindlimb (b, e, black arrowheads), pelvic girdle (e, black arrow), and vertebral mesenchyme (c, black arrowheads) and at E12.5 and E13.5 in vertebral cartilages, such as the centrum (f, red arrow), transverse processes (f, black arrows), laminae (f, black arrowhead), and neural arches (g, black arrowheads). Leprel1, while absent from forelimb (h, empty black arrowhead) and hindlimb buds (i, empty black arrowhead) at E12.5, was present at low levels in these tissues (k and l, red arrowheads respectively) and the pelvic girdle (l, red arrow) at E13.5. In addition, it was present in the olfactory epithelium (j, black arrowhead) at E12.5, as well as in the cartilage of the vertebral centra (m, red arrow) at E13.5. Leprel2 was expressed in forelimb bud (n, black arrowhead), hindlimb bud (r, black arrowhead), mandibular pre-cartilaginous mesenchyme (o, black arrowhead), tissues of the eye (p, black arrowhead), olfactory epithelium (q, black arrowhead), neural arch cartilages (s, black arrowheads), dorsal root ganglia (s, black arrows), and the epithelium and nephrogenic mesenchyme of the developing kidney (t, red and blue insets, respectively, black arrowheads).

Copyright

This image is from Capellini TD, Genesis 2008 Nov;46(11):683-96, and is displayed with the permission of Wiley-Blackwell, who owns the Copyright.

Associated
Assays

Label	Assay & Result Details (Gene Symbol)	Spatial Mapping
a' Leprecan E10.5	MGI:5295408 (P3h1)
a' Leprecan E11.5	MGI:5295408 (P3h1)
a' Leprecan E12.5	MGI:5295408 (P3h1)
a' Leprecan E13.5	MGI:5295408 (P3h1)
a' Leprecan-like1 E10.5	MGI:5295412 (P3h2)
a' Leprecan-like1 E11.5	MGI:5295412 (P3h2)
a' Leprecan-like1 E12.5	MGI:5295412 (P3h2)
a' Leprecan-like1 E13.5	MGI:5295412 (P3h2)
a' Leprecan-like2 E10.5	MGI:5295413 (P3h3)
a' Leprecan-like2 E11.5	MGI:5295413 (P3h3)
a' Leprecan-like2 E12.5	MGI:5295413 (P3h3)
a' Leprecan-like2 E13.5	MGI:5295413 (P3h3)
b'a	MGI:5295408 (P3h1)
b'b	MGI:5295408 (P3h1)
b'c	MGI:5295408 (P3h1)
b'd	MGI:5295408 (P3h1)
b'e	MGI:5295408 (P3h1)
b'f	MGI:5295408 (P3h1)
b'g	MGI:5295408 (P3h1)
b'h	MGI:5295412 (P3h2)
b'i	MGI:5295412 (P3h2)
b'j	MGI:5295412 (P3h2)
b'k	MGI:5295412 (P3h2)
b'l	MGI:5295412 (P3h2)
b'm	MGI:5295412 (P3h2)
b'n	MGI:5295413 (P3h3)
b'o	MGI:5295413 (P3h3)
b'p	MGI:5295413 (P3h3)
b'q	MGI:5295413 (P3h3)
b'r	MGI:5295413 (P3h3)
b's	MGI:5295413 (P3h3)
b't	MGI:5295413 (P3h3)