Phenotype Image Detail

Image

Caption

B: Wild-type (YB-1^+/+) and Ybx1^tm1Tuch/Ybx1^tm1Tuch (YB-1^-/-) embryos at E11.5 to E14.5 stages of development. Exencephaly was observed in various embryonic stages of mutant mice. Arrow indicates brain tissue outside of the calvarium in exencephalic embryos. C: Wild-type and mutant embryos at E10.5 stage of development. Mutant embryos show severe hemorrhage (bottom left panel) and anemia (bottom right panel) in comparison with wild-type embryos (top panels).

Copyright

This image is from Uchiumi T, J Biol Chem 2006 Dec 29;281(52):40440-9 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:117725

Associated Alleles

Symbol	Name
Ybx1^tm1Tuch	Y box protein 1; targeted mutation 1, Takeshi Uchiumi

Associated Genotypes

Allelic Composition	Genetic Background
Ybx1^tm1Tuch/Ybx1^tm1Tuch	involves: 129S/SvEv * C57BL/6