Phenotype Image Detail

Image

Caption

A and B: Alizarin red S and Alcian blue staining of hindlimbs of P21 (A) and 7 month old (B) mice. Genotypes as indicated. C-H: Rib cages of P21 (C and D), 5 (E and F), and 7 month old (G and H) mice. F is an enlarged view of E showing accumulation of bony material in sternum joints. Arrows point to abnormally formed bones of mutant mice. I and J: Angular defects of tarsal bones in P21 mouse.

Copyright

This image is from Yang X, J Cell Biol 2001 Apr 2;153(1):35-46, and is displayed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported License. J:68792

Associated Alleles

Symbol	Name
Smad3^tm1Cxd	SMAD family member 3; targeted mutation 1, Chu-Xia Deng

Associated Genotypes

Allelic Composition	Genetic Background
Smad3^tm1Cxd/Smad3^tm1Cxd	involves: 129S6/SvEvTac