Phenotype Image Detail

Image

Caption

Phenotypic characterization of bone marrow-derived cells from wild-type and Srgn^tm1Mabr/Srgn^tm1Mabr mice. A: Effect of stem cell factor (SCF) on bone marrow-derived cells. Bone marrow cells from wild-type (+/+) and Srgn^tm1Mabr/Srgn^tm1Mabr (-/-) littermates were first incubated for 4 weeks (4w) with WEHI-3B-conditioned medium, after which SCF was added to the culture medium. Cytospin slides were prepared after 7 days and were stained with May Grunwald/Giemsa. B: c-Kit expression. Bone marrow cells were cultured for 4 weeks with WEHI-3B-conditioned medium and were further cultured for 1 week (1w), either in the absence (upper panel) or presence (lower panel) of SCF. Cytospin slides were prepared and were immunostained with an anti-c-Kit monoclonal antibody.

Copyright

This image is from Abrink M, J Biol Chem 2004 Oct 24;279(39):40897-905 and is displayed with the permission of the American Society for Biochemistry and Molecular Biology who owns the Copyright. Full text from JBC. J:93338

Associated Alleles

Symbol	Name
Srgn^tm1Mabr	serglycin; targeted mutation 1, Magnus Abrink

Associated Genotypes

Allelic Composition	Genetic Background
Srgn^tm1Mabr/Srgn^tm1Mabr	involves: 129X1/SvJ