Phenotype Image Detail

Image

Caption

Abnormal foot-clasping reflex in Jph3^tm1Hta/Jph3^tm1Hta Jph4^tm1Hta/Jph4^tm1Hta mice. Wild type mice open their hindlimbs when suspended by the tail (left). However, the double homozygous mutant mice cross their legs when hung upside-down (right).

Copyright

This image is from Moriguchi S, Proc Natl Acad Sci U S A 2006 Jul 11;103(28):10811-6. Copyright 2006 National Academy of Sciences, U.S.A. J:111805

Associated Alleles

Symbol	Name
Jph3^tm1Hta	junctophilin 3; targeted mutation 1, Hiroshi Takeshima
Jph4^tm1Hta	junctophilin 4; targeted mutation 1, Hiroshi Takeshima

Associated Genotypes

Allelic Composition	Genetic Background
Jph3^tm1Hta/Jph3^tm1Hta Jph4^tm1Hta/Jph4^tm1Hta	involves: 129S4/SvJae * C57BL/6J