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Phenotype Image Detail
Image
Caption Compared with the wild-type mouse (left), the Sox9tm2Crm/Sox9tm2Crm H2az2Tg(Wnt1-cre)11Rth/0 skeleton shows obvious craniofacial deformities characterized as a domed skull and short snout. However, no abnormalities are seen in the trunk or limbs.
Copyright This image is from Mori-Akiyama Y, Proc Natl Acad Sci U S A 2003 Aug 5;100(16):9360-5. Copyright 2003 National Academy of Sciences, U.S.A. J:84790
Associated
Alleles
Symbol Name
H2az2Tg(Wnt1-cre)11Rth H2A.Z histone variant 2; transgene insertion 11, David H Rowitch
Sox9tm2Crm SRY (sex determining region Y)-box 9; targeted mutation 2, Benoit de Crombrugghe
Associated
Genotypes
Allelic Composition Genetic Background
Sox9tm2Crm/Sox9tm2Crm
H2az2Tg(Wnt1-cre)11Rth/H2az2+ 		involves: 129S7/SvEvBrd * C57BL/6 * CBA
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory