Phenotype Image Detail

Image

Caption

Hematoxylin and eosin-stained equivalent coronal sections of brains of three littermate fetal mice taken at the level of the optic chiasm. The brain from a +/+ wild-type is shown in panel A, brains of two of its Marcks^tm1Pjb/Marcks^tm1Pjb littermates are shown in panels B & C. The * indicates structures equivalent to Porbst's bundles that have formed due to failure of formation of the ventral hippocampal commissures. Appreviations: optic chiasm (o); Marginal zone (m); corpus callosum (c); ventral hippocampal commissure (v); anterior commissure (a); Probst's bundles (p). Scalebar: 0.5mm

Copyright

This image is from Stumpo DJ, Proc Natl Acad Sci U S A 1995 Feb 14;92(4):944-8. Copyright 1995 National Academy of Sciences, U.S.A. J:22949

Associated Alleles

Symbol	Name
Marcks^tm1Pjb	myristoylated alanine rich protein kinase C substrate; targeted mutation 1, Perry J Blackshear

Associated Genotypes

Allelic Composition	Genetic Background
Marcks^tm1Pjb/Marcks^tm1Pjb	involves: 129P2/OlaHsd * C57BL/6J