Gene Expression Image Detail

Reference

Figure

ID

J:36834 Torres M, et al., Development. 1996 Nov;122(11):3381-91

4

MGI:1345495

Image

Caption

(B) asterisk, optic fissure; arrowhead, pigmented epithelium of the optic cup; arrow, dorsal regions of the stalk. (C) arrowhead, pigmented retinal cells. (D) A magnification of B. asterisk, invaginated tissue of ventral origin; arrowheads, pigmentation not in Pax2-expressing cells. (E) A histological section at E17 at the insertion of the optic nerve into the eye cup in a control embryo. The pigmented retina shows a clear limit with respect to the optic nerve (arrowheads). Cells of the former optic stalk have proliferated and differentiated into Glial cells of the optic nerve. A similar section of the mutant eye (F) shows that the pigmented cell phenotype has extended into the optic stalk region and thus surrounds the optic nerve. (G,H) Sections of, respectively, control and mutant optic nerves in the way to the diencephalon. Note the abnormal coating of the mutant optic nerve by pigmented cells as well as the absence of glial cells in F and H. le, lens; nr, neural retina; pr, pigmented retina; on, optic nerve.

Copyright

This image is from Torres, et al., Development 122:3381-3391 (1996), and is displayed with the permission of The Company of Biologists Limited who owns the Copyright.

Associated
Assays

Label	Assay & Result Details (Gene Symbol)	Spatial Mapping
B	MGI:1345515 (Pax2)
C	MGI:1345519 (Pax2)
D	MGI:1345519 (Pax2)