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Gene Expression Data
Assay Details
Assay
Reference: J:36834 Torres M, et al., Pax2 contributes to inner ear patterning and optic nerve trajectory. Development. 1996 Nov;122(11):3381-91
Assay type: RNA in situ
MGI Accession ID: MGI:1345515
Gene symbol: Pax2
Gene name: paired box 2
Probe: Pax2 cDNA3
Probe preparation: Antisense RNA
Results
Specimen 3E: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: retina Present Regionally restricted 3E At this stage, transcripts are restricted to the converging lips of the retina on both sides of the optic fissure.

Specimen 4B: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: optic stalk Present Regionally restricted 4B Only in the optic stalk region, continuous to the pigmented epithelium of the optic cup, the expression extends to dorsal regions of the stalk. The limit is sharply defined such that no cell expressing Pax2 shows pigmentation.
TS20: optic fissure Present Regionally restricted 4B Ventral expression at the optic fissure extends from the distal regions to the basis of the diencephalon.
TS20: diencephalon Absent 4B
TS20: pigmented retinal epithelium Absent 4B

Specimen 6C: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: optic stalk Present 6C
TS15: diencephalon Absent 6C

Specimen 6H: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: diencephalon Present Regionally restricted 6H Pax2 expression has extended medially into the gap left by Shh, so that the expression pattern is now continuous ventrally, yet still not overlapping the Shh expression domain.
TS19: optic recess Present Regionally restricted 6H Pax2 expression has extended medially into the gap left by Shh, so that the expression pattern is now continuous ventrally, yet still not overlapping the Shh expression domain.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory